Antiretroviral treatment reduces increased CSF neurofilament protein (NFL) in HIV-1 infection
October 9th, 2007
Neurology September 9, 2007
“Conclusion: HAART seems to halt the neurodegenerative process(es) caused by HIV-1, as shown by the significant decrease in CSF NFL after treatment initiation. CSF NFL may serve as a useful marker in monitoring CNS injury in HIV-1 infection and in evaluating CNS efficacy of antiretroviral therapy.”
Comment: It has long been observed that antiretroviral treatment can prevent or reverse HIV dementia in many cases. This study helps in understanding some of the mechanism, and may make possible a blood test to see who is at risk, and how well their treatment is working.
Entry Filed under: HIV Medication
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